Hailey-Hailey disease (HHD) is a rare autosomal dominant acantholytic dermatosis.It is characterized by a recurrent eruption of vesicles, erosions, and scaly erythematous plaques involving intertriginous areas and first occurring after puberty, mostly in the third melee live resin or fourth decade.In 2000, mutations in the ATP2C1 gene on band 3q22.
Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis.The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood.Methods Circular RNA hsa_circ_0001681 (termed Circ-RAPGEF5 hereafter) was identified by circular RNA sequencing from 19
Makna Gramatikal Punning Phrase Dajare dalam Kanal Youtube Shakishakinashi-Zu
Dajare is a kind of Japanese wordplay in which a bad or unfunny joke is created by using the same or similar-sounding phrases or words.This uniqueness makes dajare interesting to analyze further in terms of its grammatical meaning crewman talc of punning phrase dajare.The source of the data used in this study is a YouTube channel about Japanese pre
Multifocal fatty liver nodules mimicking a metastatic disease: A case report
Multifocal fatty liver nodules can present a diagnostic challenge due to their resemblance to metastatic liver disease.This case report illustrates the complexity of such scenarios through the presentation of a middle-aged male patient.Despite the common nature of fatty liver disease, characterized by hepatocyte fat accumulation leading to diffuse
Influence of application methods of one-step self-etching adhesives on microtensile bond strength
Objectives The purpose of this study was to evaluate the effect of various application methods of one-step self-etch adhesives to microtensile resin-dentin bond strength.Materials and Methods Thirty-six extracted human molars were used.The teeth were assigned randomly to twelve groups (n = 15), according to the three different adhesive systems (Cle